- The film coincides with the 75th anniversary of Captain America. 2016 also marks the 10th anniversary of the original Civil War comic book and Black Panther's 50th anniversary.
- This was the longest Marvel film, at two hours and twenty-seven minutes, until "Infinity War" (2 hours 35 mins).
- This movie marks the beginning of Phase Three in the Marvel Cinematic Universe, and is the thirteenth film overall.
- (at around 1h 24 mins) Wanda (Scarlet Witch) can disable the Vision, because she received her powers from the mind stone. One of Vision's powers, is to manipulate his body density, so he can become phantasmal, or stronger than diamonds. She made him so dense, that he became too heavy to move, and fell through the floor.
- A large part of the film is set in Romania, where Sebastian Stan, who plays Bucky Barnes, a.k.a. Winter Soldier, was born.
- In Spain, the film was titled "Capitán América: Civil War". The decision for not translating the subtitle "Civil War" as "Guerra Civil" was an attempt to avoid links or comparisons with the Spanish Civil War (plainly named in the country as "Guerra Civil"), which was fought between July 17, 1936 and April 1, 1939.
- Vision: [straining] If you do this, they will never stop being afraid of you.
Wanda Maximoff: I can't control their fear. Only my own.
- Vision: A pinch of paprika... A pinch...
Wanda Maximoff: Is that Paprikash?
Vision: I thought it might lift your spirits.
Wanda Maximoff: [Tastes Vision's cooking] Spirits lifted.
Vision: In my defense, I haven't actually eaten anything before, so... please... Wanda?
Wanda Maximoff: Hmm?
Vision: No one dislikes you.
Wanda Maximoff: [Chuckles] Thanks.
Vision: Oh you're welcome. No. It's ah... involuntary response in their amygdala that can't help but being afraid of you.
Wanda Maximoff: Are you?
Vision: My amygdala is synthetic, so...
Wanda Maximoff: [laugh] ... I used to think of myself one way. But after this
[swirling fingers with magic]
Wanda Maximoff: I am something else. And still me, I think. But that's not what everyone else sees.
Vision: Do you know, I don't know what this is
[point at mind gem on his forehead]
Vision: . Not really. I know it's not of this world. But it powered Loki staff, gave you your abilities. But its true nature is a mystery. And yet, it is part of me.
Wanda Maximoff: Are you afraid of it?
Vision: I wish to understand it. The more I do the less it controls me. One day, who knows, I may even control it.
Wanda Maximoff: [Back at Vision's cooking] I don't know what's in this but it's not paprika. I'm gonna go to the store i'll be back in 20 minutes.
Vision: Alternatively, we could order a pizza?
Wanda Maximoff: Vision, are you not letting me leave?
Vision: ...It is a question of safety.
Wanda Maximoff: I can protect myself.
Vision: Not yours. Mr. Stark would like to avoid the possibility of another public incident. Until the Accords are a more secured foundation
Wanda Maximoff: ...And what do you want? Vision: For people to see you... as I do.
- Wanda Maximoff: What about the gas?
Steve Rogers: Get it out.
Principal photography began on April 27, 2015, in Fayette County, Georgia, at Pinewood Atlanta Studios, under the working title Sputnik. Other filming locations in the Atlanta metropolitan area included the Buckhead district of Atlanta; the Peachtree Christian Church in Midtown Atlanta; Downtown Atlanta,including an area near Philips Arena known as The Gulch, which served as the market in Lagos; Norcross, Georgia; Porsche's headquarters in Atlanta at Aerotropolis Atlanta, which served as the Avengers' headquarters in the film; and the Atlanta Civic Center, which served as the IFID (Institute for Infectious Diseases) laboratory in Lagos; the latter's interiors doubled as MIT, and a third part was used for a Berlin location. After the reveal of the film's full cast, many outlets and fans began referring to the film as "Avengers 2.5 ", given the variety and ensemble nature of the cast, usually reserved for the Avengers films, and the fact that the film no longer felt like a Captain America-centric one, as with The Winter Soldier. In response to this, Feige said, "What's fun about Civil War though is, as you know from the comics, it's a very simple story. And it really has to be, to accommodate that many players. It's very much a Captain America movie and it's very much a sequel to the Winter Soldier in ways I don't think people [will expect].... It's a very simple structure that allows you to have these amazing character interactions in a way that I don't think becomes overwhelming." By the end of June, filming reached the halfway mark, with production moving to Germany in early August. Filming locations in Germany included the Olympic Stadium in Berlin, and the Leipzig/Halle Airport in Schkeuditz. Additional filming also took place in Puerto Rico and Norway, and was scheduled to in Iceland. Principal photography wrapped on August 22, 2015. Captain America: Civil War was the first film to use IMAX's digital 2D cameras, made in partnership with Arri, which was a customized version of the Arri Alexa 65.
Captain America: Civil War premiered at the Dolby Theatre in Hollywood on April 12, 2016, and was screened at CinemaCon 2016 on April 13. The film's Southeast Asia premiere was held on April 21 at the Marina Bay Sands resort in Singapore, while the European premiere took place at Vue Cinemas in Westfield London on April 26. The film was released internationally starting from April 27, releasing in 61 countries its first weekend, including the United Kingdom on April 29. The North America release on May 6, took place in over 4,200 theaters, of which 3,300 were in 3D, along with 378 IMAX theaters, 480 premium large-format, and 161 D-Box locations. Internationally, the film opened in 955 IMAX theaters, while South Korea saw Civil War open in an "unprecedented" 1,989 theaters.